Map drawn by Amache High School student Eddie Kubota.

The central section of Camp Amache was 640 acres (one square mile), made up primarily of 29 blocks of Army-style barracks. Each block had a mess hall, laundry, toilets, and a shower room. There were also shared administrative facilities such as a hospital, school, recreation buildings, a public library, dry goods store, barber shop, sewage plant, and post office. The internees made improvements to the center and responded by constructing three koi ponds and gardens, and planting trees between rows of barracks.

A barbed wire fence surrounded the central section of the center with six watch towers along the perimeter. As in most of the relocation centers, armed military police manned the towers.